Atypical angiopoietin-like protein that regulates ANGPTL3
نویسندگان
چکیده
منابع مشابه
Atypical angiopoietin-like protein that regulates ANGPTL3.
Angiopoietin-like proteins (ANGPTLs) play major roles in the trafficking and metabolism of lipids. Inactivation of ANGPTL3, a gene located in an intron of DOCK7, results in very low levels of LDL-cholesterol (C), HDL-C and triglyceride (TAG). We identified another ANGPTL family member, ANGPTL8, which is located in the corresponding intron of DOCK6. A variant in this family member (rs2278426, R5...
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‡The Department of Medicine and Pathophsiology, Graduate School of Frontier Bioscience and Graduate School of Medicine, Osaka University, 2-2 Yamadaoka, Suita, Osaka 565-0871; †Pharmacology and Molecular Biology Research Laboratories and ‡‡Biomedical Research Laboratories, Sankyo Co., Ltd. 2-58 Hiromachi 1-tyome, Shinagawa-ku, Tokyo 140-8710; ††Medical Safety Research Laboratories, Sankyo Co., ...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2012
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.1217552109